A general approach for predicting protein epitopes targeted by antibody repertoires using whole proteomes
Identifieur interne : 000728 ( Main/Exploration ); précédent : 000727; suivant : 000729A general approach for predicting protein epitopes targeted by antibody repertoires using whole proteomes
Auteurs : Michael L. Paull ; Tim Johnston ; Kelly N. Ibsen ; Joel D. Bozekowski ; Patrick S. DaughertySource :
- PLoS ONE [ 1932-6203 ] ; 2019.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Algorithmes, Analyse de séquence de protéine (), Anticorps (), Anticorps (immunologie), Antigènes bactériens (), Antigènes bactériens (immunologie), Antigènes viraux (), Antigènes viraux (immunologie), Enfant, Enterovirus (immunologie), Humains, Protéome (), Protéome (immunologie), Protéomique (), Staphylococcus (immunologie), Streptococcus (immunologie), Sujet âgé, Épitopes (), Épitopes (immunologie).
- MESH :
- immunologie : Anticorps, Antigènes bactériens, Antigènes viraux, Enterovirus, Protéome, Staphylococcus, Streptococcus, Épitopes.
- Adolescent, Adulte, Adulte d'âge moyen, Algorithmes, Analyse de séquence de protéine, Anticorps, Antigènes bactériens, Antigènes viraux, Enfant, Humains, Protéome, Protéomique, Sujet âgé, Épitopes.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Algorithms, Antibodies (chemistry), Antibodies (immunology), Antigens, Bacterial (chemistry), Antigens, Bacterial (immunology), Antigens, Viral (chemistry), Antigens, Viral (immunology), Child, Enterovirus (immunology), Epitopes (chemistry), Epitopes (immunology), Humans, Middle Aged, Proteome (chemistry), Proteome (immunology), Proteomics (methods), Sequence Analysis, Protein (methods), Staphylococcus (immunology), Streptococcus (immunology).
- MESH :
- chemical , chemistry : Antibodies, Antigens, Bacterial, Antigens, Viral, Epitopes, Proteome.
- chemical , immunology : Antibodies, Antigens, Bacterial, Antigens, Viral, Epitopes, Proteome.
- immunology : Enterovirus, Staphylococcus, Streptococcus.
- methods : Proteomics, Sequence Analysis, Protein.
- Adolescent, Adult, Aged, Algorithms, Child, Humans, Middle Aged.
Abstract
Antibodies are essential to functional immunity, yet the epitopes targeted by antibody repertoires remain largely uncharacterized. To aid in characterization, we developed a generalizable strategy to predict antibody-binding epitopes within individual proteins and entire proteomes. Specifically, we selected antibody-binding peptides for 273 distinct sera out of a random library and identified the peptides using next-generation sequencing. To predict antibody-binding epitopes and the antigens from which these epitopes were derived, we tiled the sequences of candidate antigens into short overlapping subsequences of length k (k-mers). We used the enrichment over background of these k-mers in the antibody-binding peptide dataset to predict antibody-binding epitopes. As a positive control, we used this approach, termed K-mer Tiling of Protein Epitopes (K-TOPE), to predict epitopes targeted by monoclonal and polyclonal antibodies of well-characterized specificity, accurately recovering their known epitopes. K-TOPE characterized a commonly targeted antigen from
Url:
DOI: 10.1371/journal.pone.0217668
PubMed: 31490930
PubMed Central: 6730857
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 001052
- to stream Pmc, to step Curation: 001052
- to stream Pmc, to step Checkpoint: 000422
- to stream PubMed, to step Corpus: 000433
- to stream PubMed, to step Curation: 000433
- to stream PubMed, to step Checkpoint: 000694
- to stream Ncbi, to step Merge: 002328
- to stream Ncbi, to step Curation: 002328
- to stream Ncbi, to step Checkpoint: 002328
- to stream Main, to step Merge: 000731
- to stream Main, to step Curation: 000728
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A general approach for predicting protein epitopes targeted by antibody repertoires using whole proteomes</title>
<author><name sortKey="Paull, Michael L" sort="Paull, Michael L" uniqKey="Paull M" first="Michael L." last="Paull">Michael L. Paull</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Johnston, Tim" sort="Johnston, Tim" uniqKey="Johnston T" first="Tim" last="Johnston">Tim Johnston</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ibsen, Kelly N" sort="Ibsen, Kelly N" uniqKey="Ibsen K" first="Kelly N." last="Ibsen">Kelly N. Ibsen</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bozekowski, Joel D" sort="Bozekowski, Joel D" uniqKey="Bozekowski J" first="Joel D." last="Bozekowski">Joel D. Bozekowski</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Daugherty, Patrick S" sort="Daugherty, Patrick S" uniqKey="Daugherty P" first="Patrick S." last="Daugherty">Patrick S. Daugherty</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">31490930</idno>
<idno type="pmc">6730857</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730857</idno>
<idno type="RBID">PMC:6730857</idno>
<idno type="doi">10.1371/journal.pone.0217668</idno>
<date when="2019">2019</date>
<idno type="wicri:Area/Pmc/Corpus">001052</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001052</idno>
<idno type="wicri:Area/Pmc/Curation">001052</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001052</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000422</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000422</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:31490930</idno>
<idno type="wicri:Area/PubMed/Corpus">000433</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000433</idno>
<idno type="wicri:Area/PubMed/Curation">000433</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000433</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000694</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000694</idno>
<idno type="wicri:Area/Ncbi/Merge">002328</idno>
<idno type="wicri:Area/Ncbi/Curation">002328</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">002328</idno>
<idno type="wicri:Area/Main/Merge">000731</idno>
<idno type="wicri:Area/Main/Curation">000728</idno>
<idno type="wicri:Area/Main/Exploration">000728</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">A general approach for predicting protein epitopes targeted by antibody repertoires using whole proteomes</title>
<author><name sortKey="Paull, Michael L" sort="Paull, Michael L" uniqKey="Paull M" first="Michael L." last="Paull">Michael L. Paull</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Johnston, Tim" sort="Johnston, Tim" uniqKey="Johnston T" first="Tim" last="Johnston">Tim Johnston</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ibsen, Kelly N" sort="Ibsen, Kelly N" uniqKey="Ibsen K" first="Kelly N." last="Ibsen">Kelly N. Ibsen</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bozekowski, Joel D" sort="Bozekowski, Joel D" uniqKey="Bozekowski J" first="Joel D." last="Bozekowski">Joel D. Bozekowski</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Daugherty, Patrick S" sort="Daugherty, Patrick S" uniqKey="Daugherty P" first="Patrick S." last="Daugherty">Patrick S. Daugherty</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">PLoS ONE</title>
<idno type="eISSN">1932-6203</idno>
<imprint><date when="2019">2019</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Algorithms</term>
<term>Antibodies (chemistry)</term>
<term>Antibodies (immunology)</term>
<term>Antigens, Bacterial (chemistry)</term>
<term>Antigens, Bacterial (immunology)</term>
<term>Antigens, Viral (chemistry)</term>
<term>Antigens, Viral (immunology)</term>
<term>Child</term>
<term>Enterovirus (immunology)</term>
<term>Epitopes (chemistry)</term>
<term>Epitopes (immunology)</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Proteome (chemistry)</term>
<term>Proteome (immunology)</term>
<term>Proteomics (methods)</term>
<term>Sequence Analysis, Protein (methods)</term>
<term>Staphylococcus (immunology)</term>
<term>Streptococcus (immunology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Algorithmes</term>
<term>Analyse de séquence de protéine ()</term>
<term>Anticorps ()</term>
<term>Anticorps (immunologie)</term>
<term>Antigènes bactériens ()</term>
<term>Antigènes bactériens (immunologie)</term>
<term>Antigènes viraux ()</term>
<term>Antigènes viraux (immunologie)</term>
<term>Enfant</term>
<term>Enterovirus (immunologie)</term>
<term>Humains</term>
<term>Protéome ()</term>
<term>Protéome (immunologie)</term>
<term>Protéomique ()</term>
<term>Staphylococcus (immunologie)</term>
<term>Streptococcus (immunologie)</term>
<term>Sujet âgé</term>
<term>Épitopes ()</term>
<term>Épitopes (immunologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Antibodies</term>
<term>Antigens, Bacterial</term>
<term>Antigens, Viral</term>
<term>Epitopes</term>
<term>Proteome</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Antibodies</term>
<term>Antigens, Bacterial</term>
<term>Antigens, Viral</term>
<term>Epitopes</term>
<term>Proteome</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Anticorps</term>
<term>Antigènes bactériens</term>
<term>Antigènes viraux</term>
<term>Enterovirus</term>
<term>Protéome</term>
<term>Staphylococcus</term>
<term>Streptococcus</term>
<term>Épitopes</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Enterovirus</term>
<term>Staphylococcus</term>
<term>Streptococcus</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Proteomics</term>
<term>Sequence Analysis, Protein</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Algorithms</term>
<term>Child</term>
<term>Humans</term>
<term>Middle Aged</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Algorithmes</term>
<term>Analyse de séquence de protéine</term>
<term>Anticorps</term>
<term>Antigènes bactériens</term>
<term>Antigènes viraux</term>
<term>Enfant</term>
<term>Humains</term>
<term>Protéome</term>
<term>Protéomique</term>
<term>Sujet âgé</term>
<term>Épitopes</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Antibodies are essential to functional immunity, yet the epitopes targeted by antibody repertoires remain largely uncharacterized. To aid in characterization, we developed a generalizable strategy to predict antibody-binding epitopes within individual proteins and entire proteomes. Specifically, we selected antibody-binding peptides for 273 distinct sera out of a random library and identified the peptides using next-generation sequencing. To predict antibody-binding epitopes and the antigens from which these epitopes were derived, we tiled the sequences of candidate antigens into short overlapping subsequences of length k (k-mers). We used the enrichment over background of these k-mers in the antibody-binding peptide dataset to predict antibody-binding epitopes. As a positive control, we used this approach, termed K-mer Tiling of Protein Epitopes (K-TOPE), to predict epitopes targeted by monoclonal and polyclonal antibodies of well-characterized specificity, accurately recovering their known epitopes. K-TOPE characterized a commonly targeted antigen from <italic>Rhinovirus A</italic>
, predicting four epitopes recognized by antibodies present in 87% of sera (n = 250). An analysis of 2,908 proteins from 400 viral taxa that infect humans predicted seven enterovirus epitopes and five Epstein-Barr virus epitopes recognized by >30% of specimens. Analysis of <italic>Staphylococcus</italic>
and <italic>Streptococcus</italic>
proteomes similarly predicted 22 epitopes recognized by >30% of specimens. Twelve of these common viral and bacterial epitopes agreed with previously mapped epitopes with p-values < 0.05. Additionally, we predicted 30 HSV2-specific epitopes that were 100% specific against HSV1 in novel and previously reported antigens. Experimentally validating these candidate epitopes could help identify diagnostic biomarkers, vaccine components, and therapeutic targets. The K-TOPE approach thus provides a powerful new tool to elucidate the organisms, antigens, and epitopes targeted by human antibody repertoires.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Amanna, Ij" uniqKey="Amanna I">IJ Amanna</name>
</author>
<author><name sortKey="Carlson, Ne" uniqKey="Carlson N">NE Carlson</name>
</author>
<author><name sortKey="Slifka, Mk" uniqKey="Slifka M">MK Slifka</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Soria Guerra, Re" uniqKey="Soria Guerra R">RE Soria-Guerra</name>
</author>
<author><name sortKey="Nieto Gomez, R" uniqKey="Nieto Gomez R">R Nieto-Gomez</name>
</author>
<author><name sortKey="Govea Alonso, Do" uniqKey="Govea Alonso D">DO Govea-Alonso</name>
</author>
<author><name sortKey="Rosales Mendoza, S" uniqKey="Rosales Mendoza S">S Rosales-Mendoza</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lemon, Sm" uniqKey="Lemon S">SM Lemon</name>
</author>
<author><name sortKey="Gates, Nl" uniqKey="Gates N">NL Gates</name>
</author>
<author><name sortKey="Simms, Te" uniqKey="Simms T">TE Simms</name>
</author>
<author><name sortKey="Bancroft, Wh" uniqKey="Bancroft W">WH Bancroft</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schellekens, Ga" uniqKey="Schellekens G">GA Schellekens</name>
</author>
<author><name sortKey="Visser, H" uniqKey="Visser H">H Visser</name>
</author>
<author><name sortKey="De Jong, Ba" uniqKey="De Jong B">BA De Jong</name>
</author>
<author><name sortKey="Van Den Hoogen, Fh" uniqKey="Van Den Hoogen F">FH Van Den Hoogen</name>
</author>
<author><name sortKey="Hazes, Jm" uniqKey="Hazes J">JM Hazes</name>
</author>
<author><name sortKey="Breedveld, Fc" uniqKey="Breedveld F">FC Breedveld</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Spatola, Bn" uniqKey="Spatola B">BN Spatola</name>
</author>
<author><name sortKey="Murray, Ja" uniqKey="Murray J">JA Murray</name>
</author>
<author><name sortKey="Kagno, M" uniqKey="Kagno M">M Kagno</name>
</author>
<author><name sortKey="Kaukinen, K" uniqKey="Kaukinen K">K Kaukinen</name>
</author>
<author><name sortKey="Daugherty, Ps" uniqKey="Daugherty P">PS Daugherty</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Elliott, Se" uniqKey="Elliott S">SE Elliott</name>
</author>
<author><name sortKey="Parchim, Nf" uniqKey="Parchim N">NF Parchim</name>
</author>
<author><name sortKey="Kellems, Re" uniqKey="Kellems R">RE Kellems</name>
</author>
<author><name sortKey="Xia, Y" uniqKey="Xia Y">Y Xia</name>
</author>
<author><name sortKey="Soffici, Ar" uniqKey="Soffici A">AR Soffici</name>
</author>
<author><name sortKey="Daugherty, Ps" uniqKey="Daugherty P">PS Daugherty</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gubin, Mm" uniqKey="Gubin M">MM Gubin</name>
</author>
<author><name sortKey="Zhang, X" uniqKey="Zhang X">X Zhang</name>
</author>
<author><name sortKey="Schuster, H" uniqKey="Schuster H">H Schuster</name>
</author>
<author><name sortKey="Caron, E" uniqKey="Caron E">E Caron</name>
</author>
<author><name sortKey="Ward, Jp" uniqKey="Ward J">JP Ward</name>
</author>
<author><name sortKey="Noguchi, T" uniqKey="Noguchi T">T Noguchi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Taylor, Tj" uniqKey="Taylor T">TJ Taylor</name>
</author>
<author><name sortKey="Brockman, Ma" uniqKey="Brockman M">MA Brockman</name>
</author>
<author><name sortKey="Mcnamee, Ee" uniqKey="Mcnamee E">EE Mcnamee</name>
</author>
<author><name sortKey="Knipe, Dm" uniqKey="Knipe D">DM Knipe</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Looker, Kj" uniqKey="Looker K">KJ Looker</name>
</author>
<author><name sortKey="Magaret, As" uniqKey="Magaret A">AS Magaret</name>
</author>
<author><name sortKey="May, Mt" uniqKey="May M">MT May</name>
</author>
<author><name sortKey="Turner, Kme" uniqKey="Turner K">KME Turner</name>
</author>
<author><name sortKey="Vickerman, P" uniqKey="Vickerman P">P Vickerman</name>
</author>
<author><name sortKey="Gottlieb, Sl" uniqKey="Gottlieb S">SL Gottlieb</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Looker, Kj" uniqKey="Looker K">KJ Looker</name>
</author>
<author><name sortKey="Magaret, As" uniqKey="Magaret A">AS Magaret</name>
</author>
<author><name sortKey="Turner, Kme" uniqKey="Turner K">KME Turner</name>
</author>
<author><name sortKey="Vickerman, P" uniqKey="Vickerman P">P Vickerman</name>
</author>
<author><name sortKey="Gottlieb, Sl" uniqKey="Gottlieb S">SL Gottlieb</name>
</author>
<author><name sortKey="Newman, Lm" uniqKey="Newman L">LM Newman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bowden, Rj" uniqKey="Bowden R">RJ Bowden</name>
</author>
<author><name sortKey="Mcgeoch, Dj" uniqKey="Mcgeoch D">DJ Mcgeoch</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gupta, R" uniqKey="Gupta R">R Gupta</name>
</author>
<author><name sortKey="Warren, T" uniqKey="Warren T">T Warren</name>
</author>
<author><name sortKey="Wald, A" uniqKey="Wald A">A Wald</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Marsden, Hs" uniqKey="Marsden H">HS Marsden</name>
</author>
<author><name sortKey="Macaulay, K" uniqKey="Macaulay K">K MacAulay</name>
</author>
<author><name sortKey="Murray, J" uniqKey="Murray J">J Murray</name>
</author>
<author><name sortKey="Smith, Iw" uniqKey="Smith I">IW Smith</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Clo, E" uniqKey="Clo E">E Clo</name>
</author>
<author><name sortKey="Kracun, Sk" uniqKey="Kracun S">SK Kracun</name>
</author>
<author><name sortKey="Nudelman, As" uniqKey="Nudelman A">AS Nudelman</name>
</author>
<author><name sortKey="Jensen, Kj" uniqKey="Jensen K">KJ Jensen</name>
</author>
<author><name sortKey="Liljeqvist, J A" uniqKey="Liljeqvist J">J-A Liljeqvist</name>
</author>
<author><name sortKey="Olofsson, S" uniqKey="Olofsson S">S Olofsson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Pan, M" uniqKey="Pan M">M Pan</name>
</author>
<author><name sortKey="Wang, X" uniqKey="Wang X">X Wang</name>
</author>
<author><name sortKey="Liao, J" uniqKey="Liao J">J Liao</name>
</author>
<author><name sortKey="Yin, D" uniqKey="Yin D">D Yin</name>
</author>
<author><name sortKey="Li, S" uniqKey="Li S">S Li</name>
</author>
<author><name sortKey="Pan, Y" uniqKey="Pan Y">Y Pan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Liu, K" uniqKey="Liu K">K Liu</name>
</author>
<author><name sortKey="Jiang, D" uniqKey="Jiang D">D Jiang</name>
</author>
<author><name sortKey="Zhang, L" uniqKey="Zhang L">L Zhang</name>
</author>
<author><name sortKey="Yao, Z" uniqKey="Yao Z">Z Yao</name>
</author>
<author><name sortKey="Chen, Z" uniqKey="Chen Z">Z Chen</name>
</author>
<author><name sortKey="Yu, S" uniqKey="Yu S">S Yu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Whitbeck, Jc" uniqKey="Whitbeck J">JC Whitbeck</name>
</author>
<author><name sortKey="Huang, Z Y" uniqKey="Huang Z">Z-Y Huang</name>
</author>
<author><name sortKey="Cairns, Tm" uniqKey="Cairns T">TM Cairns</name>
</author>
<author><name sortKey="Gallagher, Jr" uniqKey="Gallagher J">JR Gallagher</name>
</author>
<author><name sortKey="Lou, H" uniqKey="Lou H">H Lou</name>
</author>
<author><name sortKey="Ponce De Leon, M" uniqKey="Ponce De Leon M">M Ponce-de-Leon</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Risinger, C" uniqKey="Risinger C">C Risinger</name>
</author>
<author><name sortKey="S Rensen, Kk" uniqKey="S Rensen K">KK Sørensen</name>
</author>
<author><name sortKey="Jensen, Kj" uniqKey="Jensen K">KJ Jensen</name>
</author>
<author><name sortKey="Olofsson, S" uniqKey="Olofsson S">S Olofsson</name>
</author>
<author><name sortKey="Bergstrom, T" uniqKey="Bergstrom T">T Bergström</name>
</author>
<author><name sortKey="Blixt, O" uniqKey="Blixt O">O Blixt</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Georgiou, G" uniqKey="Georgiou G">G Georgiou</name>
</author>
<author><name sortKey="Ippolito, Gc" uniqKey="Ippolito G">GC Ippolito</name>
</author>
<author><name sortKey="Beausang, J" uniqKey="Beausang J">J Beausang</name>
</author>
<author><name sortKey="Busse, Ce" uniqKey="Busse C">CE Busse</name>
</author>
<author><name sortKey="Wardemann, H" uniqKey="Wardemann H">H Wardemann</name>
</author>
<author><name sortKey="Quake, Sr" uniqKey="Quake S">SR Quake</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lee, J" uniqKey="Lee J">J Lee</name>
</author>
<author><name sortKey="Boutz, Dr" uniqKey="Boutz D">DR Boutz</name>
</author>
<author><name sortKey="Chromikova, V" uniqKey="Chromikova V">V Chromikova</name>
</author>
<author><name sortKey="Joyce, Mg" uniqKey="Joyce M">MG Joyce</name>
</author>
<author><name sortKey="Vollmers, C" uniqKey="Vollmers C">C Vollmers</name>
</author>
<author><name sortKey="Leung, K" uniqKey="Leung K">K Leung</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Paull, Ml" uniqKey="Paull M">ML Paull</name>
</author>
<author><name sortKey="Daugherty, Ps" uniqKey="Daugherty P">PS Daugherty</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kringelum, Jv" uniqKey="Kringelum J">JV Kringelum</name>
</author>
<author><name sortKey="Nielsen, M" uniqKey="Nielsen M">M Nielsen</name>
</author>
<author><name sortKey="Padkj R, Sb" uniqKey="Padkj R S">SB Padkjær</name>
</author>
<author><name sortKey="Lund, O" uniqKey="Lund O">O Lund</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hecker, M" uniqKey="Hecker M">M Hecker</name>
</author>
<author><name sortKey="Fitzner, B" uniqKey="Fitzner B">B Fitzner</name>
</author>
<author><name sortKey="Wendt, M" uniqKey="Wendt M">M Wendt</name>
</author>
<author><name sortKey="Lorenz, P" uniqKey="Lorenz P">P Lorenz</name>
</author>
<author><name sortKey="Flechtner, K" uniqKey="Flechtner K">K Flechtner</name>
</author>
<author><name sortKey="Steinbeck, F" uniqKey="Steinbeck F">F Steinbeck</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Xu, Gj" uniqKey="Xu G">GJ Xu</name>
</author>
<author><name sortKey="Kula, T" uniqKey="Kula T">T Kula</name>
</author>
<author><name sortKey="Xu, Q" uniqKey="Xu Q">Q Xu</name>
</author>
<author><name sortKey="Li, Mz" uniqKey="Li M">MZ Li</name>
</author>
<author><name sortKey="Vernon, Sd" uniqKey="Vernon S">SD Vernon</name>
</author>
<author><name sortKey="Ndung, T" uniqKey="Ndung T">T Ndung’u</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Legutki, Jb" uniqKey="Legutki J">JB Legutki</name>
</author>
<author><name sortKey="Zhao, Z G" uniqKey="Zhao Z">Z-G Zhao</name>
</author>
<author><name sortKey="Greving, M" uniqKey="Greving M">M Greving</name>
</author>
<author><name sortKey="Woodbury, N" uniqKey="Woodbury N">N Woodbury</name>
</author>
<author><name sortKey="Johnston, Sa" uniqKey="Johnston S">SA Johnston</name>
</author>
<author><name sortKey="Stafford, P" uniqKey="Stafford P">P Stafford</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Liu, X" uniqKey="Liu X">X Liu</name>
</author>
<author><name sortKey="Hu, Q" uniqKey="Hu Q">Q Hu</name>
</author>
<author><name sortKey="Liu, S" uniqKey="Liu S">S Liu</name>
</author>
<author><name sortKey="Tallo, Lj" uniqKey="Tallo L">LJ Tallo</name>
</author>
<author><name sortKey="Sadzewicz, L" uniqKey="Sadzewicz L">L Sadzewicz</name>
</author>
<author><name sortKey="Schettine, Ca" uniqKey="Schettine C">CA Schettine</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bailey, T" uniqKey="Bailey T">T Bailey</name>
</author>
<author><name sortKey="Elkan, C" uniqKey="Elkan C">C Elkan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sykes, Kf" uniqKey="Sykes K">KF Sykes</name>
</author>
<author><name sortKey="Legutki, Jb" uniqKey="Legutki J">JB Legutki</name>
</author>
<author><name sortKey="Stafford, P" uniqKey="Stafford P">P Stafford</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Pantazes, Rj" uniqKey="Pantazes R">RJ Pantazes</name>
</author>
<author><name sortKey="Reifert, J" uniqKey="Reifert J">J Reifert</name>
</author>
<author><name sortKey="Bozekowski, J" uniqKey="Bozekowski J">J Bozekowski</name>
</author>
<author><name sortKey="Ibsen, Kn" uniqKey="Ibsen K">KN Ibsen</name>
</author>
<author><name sortKey="Murray, Ja" uniqKey="Murray J">JA Murray</name>
</author>
<author><name sortKey="Daugherty, Ps" uniqKey="Daugherty P">PS Daugherty</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bastas, G" uniqKey="Bastas G">G Bastas</name>
</author>
<author><name sortKey="Sompuram, Sr" uniqKey="Sompuram S">SR Sompuram</name>
</author>
<author><name sortKey="Pierce, B" uniqKey="Pierce B">B Pierce</name>
</author>
<author><name sortKey="Vani, K" uniqKey="Vani K">K Vani</name>
</author>
<author><name sortKey="Bogen, Sa" uniqKey="Bogen S">SA Bogen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Altschul, Sf" uniqKey="Altschul S">SF Altschul</name>
</author>
<author><name sortKey="Gish, W" uniqKey="Gish W">W Gish</name>
</author>
<author><name sortKey="Miller, W" uniqKey="Miller W">W Miller</name>
</author>
<author><name sortKey="Myers, Ew" uniqKey="Myers E">EW Myers</name>
</author>
<author><name sortKey="Lipman, Dj" uniqKey="Lipman D">DJ Lipman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Richer, J" uniqKey="Richer J">J Richer</name>
</author>
<author><name sortKey="Johnston, Sa" uniqKey="Johnston S">SA Johnston</name>
</author>
<author><name sortKey="Stafford, P" uniqKey="Stafford P">P Stafford</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Larman, Hb" uniqKey="Larman H">HB Larman</name>
</author>
<author><name sortKey="Laserson, U" uniqKey="Laserson U">U Laserson</name>
</author>
<author><name sortKey="Querol, L" uniqKey="Querol L">L Querol</name>
</author>
<author><name sortKey="Verhaeghen, K" uniqKey="Verhaeghen K">K Verhaeghen</name>
</author>
<author><name sortKey="Solimini, Nl" uniqKey="Solimini N">NL Solimini</name>
</author>
<author><name sortKey="Xu, Gj" uniqKey="Xu G">GJ Xu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sundstrom, P" uniqKey="Sundstrom P">P Sundström</name>
</author>
<author><name sortKey="Nystrom, M" uniqKey="Nystrom M">M Nyström</name>
</author>
<author><name sortKey="Ruuth, K" uniqKey="Ruuth K">K Ruuth</name>
</author>
<author><name sortKey="Lundgren, E" uniqKey="Lundgren E">E Lundgren</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Samuelson, A" uniqKey="Samuelson A">A Samuelson</name>
</author>
<author><name sortKey="Forsgren, M" uniqKey="Forsgren M">M Forsgren</name>
</author>
<author><name sortKey="Johansson, Bo" uniqKey="Johansson B">BO Johansson</name>
</author>
<author><name sortKey="Wahren, B" uniqKey="Wahren B">B Wahren</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Young, Ls" uniqKey="Young L">LS Young</name>
</author>
<author><name sortKey="Rickinson, Ab" uniqKey="Rickinson A">AB Rickinson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Romero Pastrana, F" uniqKey="Romero Pastrana F">F Romero Pastrana</name>
</author>
<author><name sortKey="Neef, J" uniqKey="Neef J">J Neef</name>
</author>
<author><name sortKey="Koedijk, Dgam" uniqKey="Koedijk D">DGAM Koedijk</name>
</author>
<author><name sortKey="De Graaf, D" uniqKey="De Graaf D">D de Graaf</name>
</author>
<author><name sortKey="Duipmans, J" uniqKey="Duipmans J">J Duipmans</name>
</author>
<author><name sortKey="Jonkman, Mf" uniqKey="Jonkman M">MF Jonkman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kaplan, El" uniqKey="Kaplan E">EL Kaplan</name>
</author>
<author><name sortKey="Huwe, Bb" uniqKey="Huwe B">BB Huwe</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mortensen, R" uniqKey="Mortensen R">R Mortensen</name>
</author>
<author><name sortKey="Nissen, Tn" uniqKey="Nissen T">TN Nissen</name>
</author>
<author><name sortKey="Fredslund, S" uniqKey="Fredslund S">S Fredslund</name>
</author>
<author><name sortKey="Rosenkrands, I" uniqKey="Rosenkrands I">I Rosenkrands</name>
</author>
<author><name sortKey="Christensen, Jp" uniqKey="Christensen J">JP Christensen</name>
</author>
<author><name sortKey="Andersen, P" uniqKey="Andersen P">P Andersen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Vita, R" uniqKey="Vita R">R Vita</name>
</author>
<author><name sortKey="Overton, Ja" uniqKey="Overton J">JA Overton</name>
</author>
<author><name sortKey="Greenbaum, Ja" uniqKey="Greenbaum J">JA Greenbaum</name>
</author>
<author><name sortKey="Ponomarenko, J" uniqKey="Ponomarenko J">J Ponomarenko</name>
</author>
<author><name sortKey="Clark, Jd" uniqKey="Clark J">JD Clark</name>
</author>
<author><name sortKey="Cantrell, Jr" uniqKey="Cantrell J">JR Cantrell</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Niespodziana, K" uniqKey="Niespodziana K">K Niespodziana</name>
</author>
<author><name sortKey="Napora, K" uniqKey="Napora K">K Napora</name>
</author>
<author><name sortKey="Cabauatan, C" uniqKey="Cabauatan C">C Cabauatan</name>
</author>
<author><name sortKey="Focke Tejkl, M" uniqKey="Focke Tejkl M">M Focke-Tejkl</name>
</author>
<author><name sortKey="Keller, W" uniqKey="Keller W">W Keller</name>
</author>
<author><name sortKey="Niederberger, V" uniqKey="Niederberger V">V Niederberger</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sam Narean, J" uniqKey="Sam Narean J">J Sam Narean</name>
</author>
<author><name sortKey="Glanville, N" uniqKey="Glanville N">N Glanville</name>
</author>
<author><name sortKey="Nunn, Cm" uniqKey="Nunn C">CM Nunn</name>
</author>
<author><name sortKey="Niespodziana, K" uniqKey="Niespodziana K">K Niespodziana</name>
</author>
<author><name sortKey="Valenta, R" uniqKey="Valenta R">R Valenta</name>
</author>
<author><name sortKey="Johnston, Sl" uniqKey="Johnston S">SL Johnston</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="H Rkonen, T" uniqKey="H Rkonen T">T Härkönen</name>
</author>
<author><name sortKey="Lankinen, H" uniqKey="Lankinen H">H Lankinen</name>
</author>
<author><name sortKey="Davydova, B" uniqKey="Davydova B">B Davydova</name>
</author>
<author><name sortKey="Hovi, T" uniqKey="Hovi T">T Hovi</name>
</author>
<author><name sortKey="Roivainen, M" uniqKey="Roivainen M">M Roivainen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Roehrig, Jt" uniqKey="Roehrig J">JT Roehrig</name>
</author>
<author><name sortKey="Hunt, Ar" uniqKey="Hunt A">AR Hunt</name>
</author>
<author><name sortKey="Johnson, Aj" uniqKey="Johnson A">AJ Johnson</name>
</author>
<author><name sortKey="Hawkes, Ra" uniqKey="Hawkes R">RA Hawkes</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Weber, Lk" uniqKey="Weber L">LK Weber</name>
</author>
<author><name sortKey="Palermo, A" uniqKey="Palermo A">A Palermo</name>
</author>
<author><name sortKey="Kugler, J" uniqKey="Kugler J">J Kügler</name>
</author>
<author><name sortKey="Armant, O" uniqKey="Armant O">O Armant</name>
</author>
<author><name sortKey="Isse, A" uniqKey="Isse A">A Isse</name>
</author>
<author><name sortKey="Rentschler, S" uniqKey="Rentschler S">S Rentschler</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mcgeoch, Dj" uniqKey="Mcgeoch D">DJ McGeoch</name>
</author>
<author><name sortKey="Moss, Hwm" uniqKey="Moss H">HWM Moss</name>
</author>
<author><name sortKey="Mcnab, D" uniqKey="Mcnab D">D McNab</name>
</author>
<author><name sortKey="Frame, Mc" uniqKey="Frame M">MC Frame</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Liljeqvist, J" uniqKey="Liljeqvist J">JÅ Liljeqvist</name>
</author>
<author><name sortKey="Trybala, E" uniqKey="Trybala E">E Trybala</name>
</author>
<author><name sortKey="Svennerholm, B" uniqKey="Svennerholm B">B Svennerholm</name>
</author>
<author><name sortKey="Jeansson, S" uniqKey="Jeansson S">S Jeansson</name>
</author>
<author><name sortKey="Sjogren Jansson, E" uniqKey="Sjogren Jansson E">E Sjögren-Jansson</name>
</author>
<author><name sortKey="Bergstrom, T" uniqKey="Bergstrom T">T Bergström</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Grabowska, A" uniqKey="Grabowska A">A Grabowska</name>
</author>
<author><name sortKey="Jameson, C" uniqKey="Jameson C">C Jameson</name>
</author>
<author><name sortKey="Laing, P" uniqKey="Laing P">P Laing</name>
</author>
<author><name sortKey="Jeansson, S" uniqKey="Jeansson S">S Jeansson</name>
</author>
<author><name sortKey="Sjogren Jansson, E" uniqKey="Sjogren Jansson E">E Sjögren-Jansson</name>
</author>
<author><name sortKey="Taylor, J" uniqKey="Taylor J">J Taylor</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Oladepo, Dk" uniqKey="Oladepo D">DK Oladepo</name>
</author>
<author><name sortKey="Klapper, Pe" uniqKey="Klapper P">PE Klapper</name>
</author>
<author><name sortKey="Marsden, Hs" uniqKey="Marsden H">HS Marsden</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nilsen, A" uniqKey="Nilsen A">A Nilsen</name>
</author>
<author><name sortKey="Ulvestad, E" uniqKey="Ulvestad E">E Ulvestad</name>
</author>
<author><name sortKey="Marsden, H" uniqKey="Marsden H">H Marsden</name>
</author>
<author><name sortKey="Langeland, N" uniqKey="Langeland N">N Langeland</name>
</author>
<author><name sortKey="Myrmel, H" uniqKey="Myrmel H">H Myrmel</name>
</author>
<author><name sortKey="Matre, R" uniqKey="Matre R">R Matre</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Eisenberg, Rj" uniqKey="Eisenberg R">RJ Eisenberg</name>
</author>
<author><name sortKey="Long, D" uniqKey="Long D">D Long</name>
</author>
<author><name sortKey="Ponce De Leon, M" uniqKey="Ponce De Leon M">M Ponce de Leon</name>
</author>
<author><name sortKey="Matthews, Jt" uniqKey="Matthews J">JT Matthews</name>
</author>
<author><name sortKey="Spear, Pg" uniqKey="Spear P">PG Spear</name>
</author>
<author><name sortKey="Gibson, Mg" uniqKey="Gibson M">MG Gibson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kalimo, Ko" uniqKey="Kalimo K">KO Kalimo</name>
</author>
<author><name sortKey="Marttila, Rj" uniqKey="Marttila R">RJ Marttila</name>
</author>
<author><name sortKey="Granfors, K" uniqKey="Granfors K">K Granfors</name>
</author>
<author><name sortKey="Viljanen, Mk" uniqKey="Viljanen M">MK Viljanen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Carmona, Sj" uniqKey="Carmona S">SJ Carmona</name>
</author>
<author><name sortKey="Nielsen, M" uniqKey="Nielsen M">M Nielsen</name>
</author>
<author><name sortKey="Schafer Nielsen, C" uniqKey="Schafer Nielsen C">C Schafer-Nielsen</name>
</author>
<author><name sortKey="Mucci, J" uniqKey="Mucci J">J Mucci</name>
</author>
<author><name sortKey="Altcheh, J" uniqKey="Altcheh J">J Altcheh</name>
</author>
<author><name sortKey="Balouz, V" uniqKey="Balouz V">V Balouz</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kim, T" uniqKey="Kim T">T Kim</name>
</author>
<author><name sortKey="Tyndel, Ms" uniqKey="Tyndel M">MS Tyndel</name>
</author>
<author><name sortKey="Huang, H" uniqKey="Huang H">H Huang</name>
</author>
<author><name sortKey="Sidhu, Ss" uniqKey="Sidhu S">SS Sidhu</name>
</author>
<author><name sortKey="Bader, Gd" uniqKey="Bader G">GD Bader</name>
</author>
<author><name sortKey="Gfeller, D" uniqKey="Gfeller D">D Gfeller</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Liu, H" uniqKey="Liu H">H Liu</name>
</author>
<author><name sortKey="Han, F" uniqKey="Han F">F Han</name>
</author>
<author><name sortKey="Zhou, H" uniqKey="Zhou H">H Zhou</name>
</author>
<author><name sortKey="Yan, X" uniqKey="Yan X">X Yan</name>
</author>
<author><name sortKey="Kosik, Ks" uniqKey="Kosik K">KS Kosik</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Halperin, Rf" uniqKey="Halperin R">RF Halperin</name>
</author>
<author><name sortKey="Stafford, P" uniqKey="Stafford P">P Stafford</name>
</author>
<author><name sortKey="Emery, Js" uniqKey="Emery J">JS Emery</name>
</author>
<author><name sortKey="Navalkar, K" uniqKey="Navalkar K">K Navalkar</name>
</author>
<author><name sortKey="Johnston, Sa" uniqKey="Johnston S">SA Johnston</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Peters, B" uniqKey="Peters B">B Peters</name>
</author>
<author><name sortKey="Sidney, J" uniqKey="Sidney J">J Sidney</name>
</author>
<author><name sortKey="Bourne, P" uniqKey="Bourne P">P Bourne</name>
</author>
<author><name sortKey="Bui, Hh" uniqKey="Bui H">HH Bui</name>
</author>
<author><name sortKey="Buus, S" uniqKey="Buus S">S Buus</name>
</author>
<author><name sortKey="Doh, G" uniqKey="Doh G">G Doh</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Caoili, Sec" uniqKey="Caoili S">SEC Caoili</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Alter Wolf, S" uniqKey="Alter Wolf S">S Alter-Wolf</name>
</author>
<author><name sortKey="Blomberg, Bb" uniqKey="Blomberg B">BB Blomberg</name>
</author>
<author><name sortKey="Riley, Rl" uniqKey="Riley R">RL Riley</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Heikkinen, T" uniqKey="Heikkinen T">T Heikkinen</name>
</author>
<author><name sortKey="J Rvinen, A" uniqKey="J Rvinen A">A Järvinen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stafford, P" uniqKey="Stafford P">P Stafford</name>
</author>
<author><name sortKey="Wrapp, D" uniqKey="Wrapp D">D Wrapp</name>
</author>
<author><name sortKey="Johnston, Sa" uniqKey="Johnston S">SA Johnston</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Burnham, Cad" uniqKey="Burnham C">CAD Burnham</name>
</author>
<author><name sortKey="Mcadam, Aj" uniqKey="Mcadam A">AJ McAdam</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stafford, P" uniqKey="Stafford P">P Stafford</name>
</author>
<author><name sortKey="Cichacz, Z" uniqKey="Cichacz Z">Z Cichacz</name>
</author>
<author><name sortKey="Woodbury, Nw" uniqKey="Woodbury N">NW Woodbury</name>
</author>
<author><name sortKey="Johnston, Sa" uniqKey="Johnston S">SA Johnston</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Palermo, A" uniqKey="Palermo A">A Palermo</name>
</author>
<author><name sortKey="Weber, Lk" uniqKey="Weber L">LK Weber</name>
</author>
<author><name sortKey="Rentschler, S" uniqKey="Rentschler S">S Rentschler</name>
</author>
<author><name sortKey="Isse, A" uniqKey="Isse A">A Isse</name>
</author>
<author><name sortKey="Sedlmayr, M" uniqKey="Sedlmayr M">M Sedlmayr</name>
</author>
<author><name sortKey="Herbster, K" uniqKey="Herbster K">K Herbster</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bozekowski, Jd" uniqKey="Bozekowski J">JD Bozekowski</name>
</author>
<author><name sortKey="Graham, Aj" uniqKey="Graham A">AJ Graham</name>
</author>
<author><name sortKey="Daugherty, Ps" uniqKey="Daugherty P">PS Daugherty</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Suzek, Be" uniqKey="Suzek B">BE Suzek</name>
</author>
<author><name sortKey="Huang, H" uniqKey="Huang H">H Huang</name>
</author>
<author><name sortKey="Mcgarvey, P" uniqKey="Mcgarvey P">P McGarvey</name>
</author>
<author><name sortKey="Mazumder, R" uniqKey="Mazumder R">R Mazumder</name>
</author>
<author><name sortKey="Wu, Ch" uniqKey="Wu C">CH Wu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ibsen, Kn" uniqKey="Ibsen K">KN Ibsen</name>
</author>
<author><name sortKey="Daugherty, Ps" uniqKey="Daugherty P">PS Daugherty</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Cock, Pja" uniqKey="Cock P">PJA Cock</name>
</author>
<author><name sortKey="Antao, T" uniqKey="Antao T">T Antao</name>
</author>
<author><name sortKey="Chang, Jt" uniqKey="Chang J">JT Chang</name>
</author>
<author><name sortKey="Chapman, Ba" uniqKey="Chapman B">BA Chapman</name>
</author>
<author><name sortKey="Cox, Cj" uniqKey="Cox C">CJ Cox</name>
</author>
<author><name sortKey="Dalke, A" uniqKey="Dalke A">A Dalke</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Pedregosa, F" uniqKey="Pedregosa F">F Pedregosa</name>
</author>
<author><name sortKey="Varoquaux, G" uniqKey="Varoquaux G">G Varoquaux</name>
</author>
<author><name sortKey="Gramfort, A" uniqKey="Gramfort A">A Gramfort</name>
</author>
<author><name sortKey="Michel, V" uniqKey="Michel V">V Michel</name>
</author>
<author><name sortKey="Thirion, B" uniqKey="Thirion B">B Thirion</name>
</author>
<author><name sortKey="Grisel, O" uniqKey="Grisel O">O Grisel</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hunter, Jd" uniqKey="Hunter J">JD Hunter</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Bozekowski, Joel D" sort="Bozekowski, Joel D" uniqKey="Bozekowski J" first="Joel D." last="Bozekowski">Joel D. Bozekowski</name>
<name sortKey="Daugherty, Patrick S" sort="Daugherty, Patrick S" uniqKey="Daugherty P" first="Patrick S." last="Daugherty">Patrick S. Daugherty</name>
<name sortKey="Ibsen, Kelly N" sort="Ibsen, Kelly N" uniqKey="Ibsen K" first="Kelly N." last="Ibsen">Kelly N. Ibsen</name>
<name sortKey="Johnston, Tim" sort="Johnston, Tim" uniqKey="Johnston T" first="Tim" last="Johnston">Tim Johnston</name>
<name sortKey="Paull, Michael L" sort="Paull, Michael L" uniqKey="Paull M" first="Michael L." last="Paull">Michael L. Paull</name>
</noCountry>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000728 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000728 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= MersV1 |flux= Main |étape= Exploration |type= RBID |clé= PMC:6730857 |texte= A general approach for predicting protein epitopes targeted by antibody repertoires using whole proteomes }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:31490930" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a MersV1
This area was generated with Dilib version V0.6.33. |